HEOR · Payers · RWE

    Build the value story without exposing the evidence.

    HTA dossiers, payer value narratives, cost-effectiveness and budget-impact models, real-world evidence on patient-level data: the work that lives under NDA and can't legally be handed to an AI. Untraceable cloaks every confidential value before the model sees a thing, so you get frontier AI on the evidence payers actually scrutinize.

    The suite, in your workflow

    Every tool, mapped to the work you already do.

    The same eight-tool suite that runs on patent-pending cloaking: pointed at HEOR, payer and RWE deliverables.

    Cloaking

    Cloak patient-level RWE, endpoints and proprietary model inputs before any AI sees them.

    Output: Sponsor-confidential values replaced with informative cloaks… meaning kept, exposure removed.

    VaultScribe

    Draft and rewrite HTA dossiers, payer value narratives and systematic-review write-ups on cloaked evidence.

    Output: Submission-ready prose fluent in HEOR and market-access conventions.

    VaultStat

    Generate pseudo-IPD and auto-produce statistical code on cloaked patient data: survival, indirect comparisons, NMA, descriptive statistics.

    Output: A statistical analysis plan and analysis code, run for you in a protected environment where the AI never sees your data, and never sees the results.

    VaultDelphi

    Pressure-test high-stakes assumptions, such as comparator choice, extrapolation, ICER drivers, across up to four models.

    Output: A report and narrative for grounded decisions: a Delphi-style consensus reached with AI, on cloaked data, giving you the evidence, the references and a traced decision narrative you can defend.

    Blueprint

    Beat the blank page on HTA and payer dossiers with compliance-aware structure.

    Output: Start from pre-filled templates: submission dossier, economic report, BIA report, built to your local guideline requirements, with AI instructions pre-generated to accelerate development.

    VaultCanvas

    Assemble cost-effectiveness and budget-impact reporting from a single Excel source of truth.

    Output: (1) Connect your Word report directly to Excel so it auto-updates with AI, the AI sees no data. Ideal for living GVDs and living economic reports, without the recurring-update hassle.(2) Generate an interactive model or deck from the PowerPoint version at the click of a button, skip time-consuming HTML/UI development and use your Excel as the interface.

    VaultChat

    Ask quick questions across a cloaked cost-effectiveness report or SLR.

    Output: Fast frontier-model answers with every value cloaked before it leaves.

    VaultAudit & Untraceable Protocol

    Certify cloaked AI use for HTA and payer scrutiny; keep an audit trail of every value, cloak and submission.

    Output: A permanent, shareable certification, stored in your project's region (United States or Canada), cloaks only, never raw values.

    The Grounding Codex

    Grounded in your field, not just a model's training data.

    VaultScribe writes on Hybrid RAG plus a Grounding Codex, a human-curated source corpus where critical guideline information is organized to augment AI intelligence while remaining human-anchored. Every entry is AI-drafted, then reviewed and iterated against a health economist's direct judgment until it holds up, not machine-scraped, not left unchecked. For HEOR that means a reference-preserving layer of 200+ entries on HTA guidelines and core HEOR methods, so the AI reasons from curated, human-vetted field references rather than training alone. The template corpus behind Blueprint is live for the United States and Canada: 1,000+ documents, including 50+ guidelines and local best-practice publications. In our controlled multi-model study, adding this knowledge layer lifted mean writing quality and, critically, improved the payer-relevant dimensions, comparative-effectiveness and completeness, while reducing hallucination on the claims payers examine most closely.

    The evidence

    We measured it, and published the numbers.

    Cloaking keeps the writing quality

    In a controlled comparison of de-identification methods, Semantic Cloaking retained 91–94/100 writing quality against a 96/100 baseline. Hiding the values instead of preserving their meaning fell to 42 out of 100 on a page with 5 hidden values, and to 18 with 22: the more you hide, the less the model has left to reason with. Meaning preserved, values never exposed.

    Read the preprint, Tremblay & Harricharan (2026) →

    Field grounding lifts quality

    Across four models, grounding in a Canadian HTA knowledge layer improved mean writing quality +2.4/100 (up to +10.0 on writing), judged by a blinded AI Delphi panel: the same consensus method behind VaultDelphi.

    Read the RAG / HTA preprint →
    See all publications →

    Put frontier AI to work on evidence you couldn't share before.

    See it on your own HEOR and payer workflow; the AI never sees a confidential value.