HEOR · Payers · RWE
HTA dossiers, payer value narratives, cost-effectiveness and budget-impact models, real-world evidence on patient-level data — the work that lives under NDA and can't legally be handed to an AI. Untraceable cloaks every confidential value before the model sees a thing, so you get frontier AI on the evidence payers actually scrutinize.
The suite, in your workflow
The same eight-tool suite that runs on patent-pending cloaking — pointed at HEOR, payer and RWE deliverables.
Cloak patient-level RWE, endpoints and proprietary model inputs before any AI sees them.
Draft and rewrite HTA dossiers, payer value narratives and systematic-review write-ups on cloaked evidence.
Generate pseudo-IPD and auto-produce statistical code on cloaked patient data — survival, indirect comparisons, NMA, descriptive statistics.
Pressure-test high-stakes assumptions — comparator choice, extrapolation, ICER drivers — across up to four models.
Beat the blank page on HTA and payer dossiers with compliance-aware structure.
Assemble cost-effectiveness and budget-impact reporting from a single Excel source of truth.
Ask quick questions across a cloaked cost-effectiveness report or SLR.
Certify cloaked AI use for HTA and payer scrutiny; keep an audit trail of every value, cloak and submission.
The Grounding Codex
VaultScribe writes on Hybrid RAG plus a Grounding Codex — a human-curated source corpus where critical guideline information is organized to augment AI intelligence while remaining human-anchored. Every entry is AI-drafted, then reviewed and iterated against a health economist's direct judgment until it holds up — not machine-scraped, not left unchecked. For HEOR that means a reference-preserving layer of 200+ entries on HTA guidelines and core HEOR methods, so the AI reasons from curated, human-vetted field references rather than training alone. In our controlled multi-model study, adding this knowledge layer lifted mean writing quality and, critically, improved the payer-relevant dimensions — comparative-effectiveness and completeness — while reducing hallucination on the claims payers examine most closely.
On our roadmap
Tracing every claim in a dossier back to its underlying real-world or clinical evidence — so a reviewer can follow any statement to its source under full HTA and payer scrutiny. This is where we're heading; it isn't a capability we claim today.
The evidence
In a controlled comparison of de-identification methods, Semantic Cloaking retained 91–94/100 writing quality against a 96/100 baseline — while censorship fell to 42 and substitution to 18. Meaning preserved, values never exposed.
Read the preprint — Tremblay & Harricharan (2026) →Across four models, grounding in a Canadian HTA knowledge layer improved mean writing quality +2.4/100 (up to +10.0 on writing), judged by a blinded AI Delphi panel — the same consensus method behind VaultDelphi.
Read the RAG / HTA preprint →See it on your own HEOR and payer workflow — the AI never sees a confidential value.